How can COVID-19 vaccines be delivered to the world at minus 20℃?

Since the outbreak, the whole world has been hit hard by the novel coronavirus. The cumulative number of confirmed cases of COVID-19 worldwide is 635 million, the death toll has exceeded 6.61 million, and the global economy is in recession. With the onset of winter in the Northern Hemisphere, the epidemic is coming back in force. By November 13, 2022, the epidemic has accelerated in South Korea, Japan and Indonesia, with 361,000 new confirmed cases in Japan, 501,000 in South Korea and 40,000 in Indonesia last week. Some countries and regions have started a new round of lockdown, hitting factories and service industries hard.

The only hope of ending this global catastrophe is a vaccine.

By November 16, 2022, a total of 12.94 billion doses of COVID-19 vaccine had been administered globally, and 3.44 billion doses of COVID-19 vaccine had been administered in China. Since the founding of the People's Republic of China, the large-scale vaccination has not only brought great pressure to vaccine manufacturers, but also raised unprecedented requirements on the scale of transportation and distribution, which will bring challenges to the global logistics industry. The supply chain for COVID-19 vaccines will be one of the more complex ever. Because "pharmaceutical cold chain transportation is called the top of the cold chain industry pyramid."

Temperature will be one of the biggest challenges in transportation. Vaccines have strict temperature control requirements. Most COVID-19 vaccines need to be stored and transported at -20℃. Any mistake in any process may cause damage to the stability and immunogenicity of vaccines. The key to COVID-19 vaccine transportation is the cold chain.

Global cold chain transport of COVID-19 vaccines presents new challenges! The WHO estimates that 50% of vaccines are wasted each year because of problems with the cold chain system. Publicly available information indicates that the Moderna vaccine is required to be stored in a 10-dose vial at normal refrigerator temperatures for Z additional 2 weeks. Once at room temperature, it must be used within 6 hours; Pfizer's vaccine, which comes in small five-dose bottles that need to be replaced with dry ice every five days, is even tougher. Refrigerate for 48 hours, at room temperature for only 6 hours.

As a number of vaccines have entered phase III clinical trials and the clinical performance of domestic inactivated vaccines has been better than expected, the advent of an effective vaccine seems imminent, and ensuring rapid and efficient transportation and distribution of vaccines is the next stop on the road to fighting the epidemic.

Based on its long-term deep cultivation and global layout in the field of life science and medical cold chain, Tengyebo is able to meet the safety and speed of COVID-19 vaccine transportation at this critical moment through the guarantee of relatively new high-tech cold chain thermostat.

Under the premise of highly strict quality management, and under the operation of an excellent team with 20 years of experience in high-end logistics, Tengyebo's rapid medical cold chain transport network has covered more than 50 countries and regions in the world, more than 200 cities above the prefectures level in China, and realized the international and domestic cold chain transport products with different timeliness from 12 hours to 168 hours. It can provide transportation of temperature control products in many temperature regions, including 0℃~30℃ (normal temperature), 2℃~8℃ (cold storage), 15℃~25℃ (constant temperature), -15℃~-25℃ (low temperature), -20℃~-86℃ (dry ice), -196℃ (liquid nitrogen), etc. It can provide comprehensive pharmaceutical cold chain logistics and supply chain services from incubator equipment, storage, ice and incubator pre-cooling, cooling, delivery, cold chain transportation, temperature record, system tracking, customs declaration, inspection, foreign trade agent.

The "Cool and cold" series of passive refrigeration international special incubator independently developed by Tengyi Boshi has reached the international leading constant temperature time, which not only meets the requirements of GSP, but also has strong insulation performance, and the insulation time can reach more than 168h, which can meet the global cold chain vaccine transportation. Good strength: after falling, vibration test, crashworthiness test. Energy saving and environmental protection: repairable, recyclable, environmental protection and pollution-free.

Operating environment: [-30℃~+80℃], insulation interval: 2~8℃, 10~20℃, 20~30℃, 15~25℃, -15~-25℃ and other warm areas (need to be equipped with the corresponding cold storage agent)

Application: It can be used in cold chain storage and transportation of medicine, vaccines, in vitro diagnostic reagents, food, etc., especially for the international transportation of drugs and vaccines.

Tengyebo has passed ISO9001 international quality standards system certification, ISO14001 international environmental standards system certification, World Customs Organization AEO certification and other strict quality, safety, information, environment, trade compliance, social responsibility and other standards certification. At present, he is a member of the Pharmaceutical Branch and the Emergency Logistics Branch of the WCA World Freight Association. He is one of the drafters of national and industry standards such as Operation Specification for Temperature Control Logistics of Medical Testing Biological Samples, Quality Management Review Specification for Pharmaceutical Logistics, Service Specification for Pharmaceutical Logistics, Operation Specification for Pharmaceutical Cold Chain Logistics, and Service Specification for Vaccine Storage and Transportation.

In terms of information system construction, Tengyi Botime has developed its own CRM system, WMS system and O/TMS system with its own intellectual property rights, ensuring efficient, safe and refined and automated management such as data traceability and visualization.

In the process of fighting COVID-19 vaccine, Tengyebo has been mobilizing all its staff. No matter during the Spring Festival or in normal times, no matter in the worst-hit Wuhan or in major hospitals, Tengyebo's staff have been fighting everywhere. From the beginning of the epidemic until now, Tengyebo has been going all out, through professional cold chain transportation of minus 20 degrees Celsius. Hundreds of millions of COVID-19 testing reagents have been delivered to all affected areas in China and around the world, making its best contribution to the global fight against the epidemic.

In the upcoming battle for global distribution of COVID-19 vaccine, be ready to fight the new battle with all your strength!